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5A) without altering BACH1 mRNA expression (Fig

In line with its ferroptosis-reducing effects, protein levels of FTH1 (ferritin heavy chain 1) were increased in a dexamethasone-dependent manner both in absence of erastin as well as upon short and long erastin exposure (Fig

Thus, in tumors, citrate (originating from reductive carboxylation of glutamine or, if applicable, OXPHOS, or acetate) does not diminish phosphofructokinase-1, the step with the highest flux-control coefficient in glycolysis

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